ND biology professors collaborate on malaria

first_img “It would take me about 2 1/2 hours to tell you malaria’s lifecycle,” Ferdig said. What makes malaria a unique parasite is that both humans and mosquitoes carry it. Biology professor Dr. Nora Besansky researches the African mosquitoes that carry human malignant malaria. Her current research examines evolutionary changes of the mosquito Anopheles Gambiae. One of the cutting edge research projects that is unique to Notre Dame is the genomic mapping of both the malaria parasite and the mosquito vector. While the human genome has already been mapped, the genomic research going on at Notre Dame is highly specialized and important to understanding infectious disease in general. Currently, there are multiple faculty members researching malaria and the mosquito vector that carries it. Together, with other researchers and scientists at Notre Dame, these biologists have been able to comprehensively look at the cause, the mosquito vector and the effect of malaria. Notre Dame’s research on malaria is a “web of interaction,” involving multidisciplinary research and collaboration, biology professor Dr. Michael Ferdig said. Besansky said when a mosquito bites a human, the parasite first enters from the bite and then travels to the liver. After it leaves the liver, the parasite attacks the red blood cells. The red blood cells than burst and the parasite can re-enter the blood stream or attack another part of the body.center_img There are four types of malaria and while all cause harm, only one, malignant malaria, is always fatal, Besansky said. What makes malaria different than other vector-carried diseases is the complex life cycle of the parasite. “Malaria is a parasitic disease that is characteristic of poorer parts of the world, especially the tropics,” Besansky said. “The mosquito can transmit the parasite to a human, but if the mosquito bites again, it can take the parasite back into its system in the blood meal,” Besansky said. Ferdig focuses on the vector, studying the parasite itself. His research looks at the malaria parasite and its resistance to drugs. “Once we know all the genes of the vector, the parasite and the human and know how they interact, we can understand how drugs would work to stop the parasite,” Ferdig said. “This is why the genome stuff is so powerful. If you can break the cycle somewhere in the malaria life cycle, you can end the disease.”last_img read more

Laura Benanti on Avoiding ‘Emotional Diarrhea’ & Her Suggestions For NBC’s Next Live Musical

first_imgBroadway fans have been singing the praises of Tony winner Laura Benanti for years, but after her hilariously shady, side-eye-filled portrayal of Baroness Elsa on NBC’s The Sound of Music, the Tony winner now has a whole new breed of fans. “I was walking in the park and a girl said to me, ‘You’re the lady from the TV. I like you so much,’” Benanti told The Los Angeles Times. “I have never felt so much love come my way in my entire career, which is hilarious to me.” Laura Benanti Now that she’s officially trended on Twitter and had a bunch of awesome GIFs made of her, Benanti is well on her way to becoming a household name—but she isn’t ready to handle full-on supertstardom. “I don’t think I’m the type of person that could go to the grocery story and have paparazzi take pictures and have people be like, ‘She looks terrible.’ I’m too sensitive,” she admitted. The key to her multi-faceted performance on the live telecast? Avoiding what Benanti calls “emotional diarrhea.” Of course! Why didn’t we think of that? “[These days], we all know what we all think at any given moment,” she says. “But if you look back in our history, there was etiquette, there was a way that people had to behave. I like to play a character who is being forced to behave a certain way but feeling something completely different underneath. To me that is the most interesting and complex character.” Well Laura, you nailed it! Star Files Until then, Benanti has a few suggestions for NBC’s next musical, and lucky for us, she could easily star in all of them: The Music Man, My Fair Lady and Mary Poppins. But if you’re hoping she’ll bat her eyes and play a traditional ingenue, you’ve got another thing coming. “Not interested,” she said. “So boring!” View Commentslast_img read more

Once Bitten: The Reality of Rabies

first_imgWhen most people see the word “rabies,” they think of rabid dogs, raccoons, skunks, and foxes. While those are certainly vectors of the viral disease, Bryan Simon, co-owner of Vertical Medicine Resources and Associate Editor for the American Alpine Club’s yearly guide, Accidents in North American Climbing, wants outdoor enthusiasts to think of bats, too.“They’re one of the most common vectors we as outdoor enthusiasts encounter here in the U.S.,” says Simon, who himself was bitten by a bat while climbing in June 2015, just a year after he wrote a report for Accidents in North American Climbing on a climber-bat incident at the Bozoo rocks in West Virginia.In nearly all instances, rabies left untreated is fatal, which is why it’s so important that patients receive post-exposure prophylaxis and human rabies immune globulin within 24 hours of the animal bite. Even more importantly, the Centers for Disease Control and Prevention recommends that anyone who even suspects having come into contact with a bat should receive the vaccine, just to be safe.Wake up after a night in an Appalachian Trail shelter and see bats roosting in the rafters? Get the vaccine. Pull your hand out of a crack, see a bat inside, but don’t feel any pain on your hand? Definitely, definitely get the vaccine.“This is not something to joke around about,” Simon says. “A lot of times people who don’t have a lot of pain, they tend to ignore the injury.”But when it comes to rabies, playing the “tough guy” card can result in loss of life.What to do:Know signs and symptoms of rabies in animals. This includes foaming at the mouth and erratic or abnormal behavior.Be aware of your surroundings. Avoid sleeping in areas where bats are known to roost or where bat guano is clearly present.Should you be planning to travel overseas to areas where rabid dogs are common, consider getting a pre-exposure rabies vaccine. “It is fairly expensive,” says Simon, “and if you’ve been bitten by an animal that you suspect has rabies, whether you’ve had the rabies vaccine or not, you still need to get to the hospital as soon as possible.” The difference in the end is two post-exposure doses versus the four you will need (plus the human rabies immune globulin) if you have not had a pre-exposure vaccine.If you so much as suspect you have been exposed to bats or other rabid animals, seek medical care immediately. “It’s a medical urgency, not emergency,” Simon adds. “I wouldn’t want someone speeding 80 miles per hour down the interstate, but you need to get out of wherever you’re at and to a hospital within 24 hours.”Call nearby hospitals to see which one carries the post-exposure prophylaxis. “Certainly don’t go to an urgent care. They’re not going to have what you need, and some hospitals even don’t carry everything. It pays to call ahead.”Wash bite site immediately with soap and copious amounts of water.Begin post-exposure prophylaxis within 24 hours of incident. Additional doses must be taken on days 3, 7, and 14 after the first vaccination.Read more about worst-case scenarios here.last_img read more

Uniondale High School Student Charged With Lunchroom Stabbing

first_imgSign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York A Uniondale High School student was arrested for stabbing a 16-year-old boy in the school lunchroom on Wednesday morning, Nassau County police said.Oscar Castaneda, 20, approached the victim, pulled out a sharp object and stabbed the victim in the neck and back, puncturing his lung at 11:39 a.m., police said.The victim was taken to a local hospital for treatment to his injuries. The alleged attacker was taken into custody.Police said there is no known motive for the attack.Castaneda was charged with assault and criminal possession of a weapon. He will be arraigned Thursday at First District Court in Hempstead.last_img

ZooMatinee: Elmira area theater group goes virtual

first_imgELMIRA, N.Y. (WBNG) — Despite the COVID-19 pandemic dropping the curtain on live theater across the region, one local theater organization is saying ‘on with the show.’ “Real people talk over each other and Zoom doesn’t let you do that it forces you to take your turn,” she said. “That is a good thing but Streamyard allows us to have more realistic conversation.” “This is a way to reach an audience that’s way beyond Corning or Elmira, New York,” he said. “We have people watching in Chicago and LA because we have friends there.” Angela Daniels, co-founder and head of the theater department at 171 Cedar Arts says the performances are made possible by a program called Streamyard. The software allows them to bring in cast members from across the country while avoiding some of the problems that come with using services such as Zoom and Microsoft Teams. ZooMatinee offers live performances every Sunday at 2 p.m. Sunday’s performance was of St. Martin’s Summer, a one-act comedy by Cosmo Hamilton. While the project was spurred by the COVID-19 crisis bringing the theater industry to a halt, Smith says he hopes the project can live on even after the crisis. You can find more information on how to watch by clicking here. “What Streamyard allows us to do is edit what the audience is seeing live and it’s tricky most of the time. It works pretty well, but every once in a while something goes wrong but it’s trial and error.” “ZooMatinee is a live performance series that is a partnership between 171 Cedar Arts Center and Elmira Little Theater; we actually broadcast live on Facebook,” said ZooMatinee Co-founder Mitchell Hurricane Smith, also a trustee at Elmira Little Theater in Elmira and Marketing and Development Manager of 171 Cedar Arts in Corning. Daniels says in addition to rehearsing and getting the shows down each week, the team faces the challenge of broadcasting a live presentation. “Whatever we get from here on out is what we build brand new and this is our piece of the new normal, this is something we can add, something we didn’t have before,” she said. At the same time she stresses that ZooMatinee is also preparing them for an industry that will be forever changed by the crisis. Daniels also says the performances have a practical purpose outside of the crisis, allowing cast and crew members who may not otherwise be able to devote a long period of time to a project like theirs to participate. last_img read more

PREMIUMASEAN Para Games postponement hurts training for Paralympics

first_imgForgot Password ? ASEAN-Para-Games ASEAN-Para-Sports-Federation coronavirus sports sporting-event LOG INDon’t have an account? Register here After previously being postponed to March this year, a regional sporting event for people with impairments, the ASEAN Para Games has been deferred indefinitely because of the coronavirus outbreak that has spread to more than 20 countries around the globe.The announcement arrived on Monday as Southeast Asia’s main organization for para sports, the ASEAN Para Sports Federation (APSF), informed Indonesia’s National Paralympic Committee (NPC) of the second postponement.After careful deliberation among executive committee members regarding “the physical and emotional well-being of all participating para athletes and staff” APSF’s board of governors secretary Osoth Bhavilai said a majority of the members had agreed that the 10th ASEAN Para Games hosted by the Philippines should be postponed indefinitely, with possible reconsideration within the year sh… Linkedin Google Facebook Log in with your social account Topics :last_img read more

Governor Wolf Announces New Apprenticeship Opportunities for the Skilled Trades in Allegheny County

first_img Economy,  Jobs That Pay,  Press Release,  Workforce Development Harrisburg, PA – Today, Governor Wolf announced the approval of three apprenticeship grants to assist with the costs of necessary classroom training for 57 apprentices in Allegheny County, enabling the recipients to strengthen and expand their apprenticeship programs. The funding, granted to the Cement Masons Local 526, the Associated Master Plumbers of Allegheny County, and J.A. Sauer Co., will build on the governor’s commitment to expanding job training opportunities for Pennsylvanians.“All across Pennsylvania, many industries in the trades have aging workforces in which increasing numbers of retirements are causing a shortage of workers,” Governor Wolf said. “But with that worker shortage comes opportunity for younger individuals to achieve high-demand, high-paying jobs in the trades. By supporting these three training programs, we’re helping to equip more workers with the skills they need to succeed in these family-sustaining careers.”Apprenticeship programs provide access to career pathways and enable apprentices to develop the knowledge, skills, and abilities necessary to compete in today’s economy. Classroom training is a required component of registered apprenticeship programs across Pennsylvania, and complements traditional on-the-job training. The technical material taught in a classroom environment enables apprentices to learn fundamental concepts, terminology, procedures, safety requirements, and basic tools and instruments.The first grant, approved for the Cement Masons Local 526 in Pittsburgh for $164,661 over three years, will support no-cost training for 25 apprentices to gain skills in the field of concrete construction. In addition to concrete finishing, forming, pouring, patching, and time management skills, the program will also educate apprentices on soft skills like financial planning and health and safety. After successful completion of the three-year program, apprentices will become journeymen earning family-sustaining wages and excellent benefits.The second grant, approved for the Associated Master Plumbers of Allegheny County (AMPAC) in Pittsburgh for $297,000 over three years, will support the training of 30 apprentices in the plumbing trade. Due to an aging workforce, southwestern Pennsylvania is experiencing a lack of skilled plumbers and a subsequent increase in costs for plumbing work. This program, which will be offered at AMPAC’s training facility in Pittsburgh, will address this need and provide workers with the skills needed to meet the area’s demand for skilled plumbers.The third grant, approved for J.A. Sauer Co. for $19,800 over three years, will support the training of two air conditioning contractor apprentices. J.A. Sauer’s program is run through the Air Conditioning Contractors of Western Pennsylvania program developed after carefully assessing the needs of the heating, ventilation, air conditioning, and refrigeration (HVACR) industry, and is taught at Pittsburgh Technical College. The funding will support the nearly 800 hours of classroom training that apprentices must complete.Apprenticeships are a key component of Governor Wolf’s PAsmart initiative, a new and innovative way to improve coordination between state agencies, cut red tape, and invest in people and business to expand innovative job training in apprenticeships and other programs so workers get the skills they need to compete in the global economy. The $30 million initiative includes $7 million to increase support for apprenticeships, with the goal of doubling the number of registered apprentices by 2025.For more information about the Wolf Administration’s commitment to workforce development, visit the Department of Community and Economic Development (DCED) website or follow us on Twitter, LinkedIn, Facebook, and YouTube. October 10, 2018 SHARE Email Facebook Twittercenter_img Governor Wolf Announces New Apprenticeship Opportunities for the Skilled Trades in Allegheny Countylast_img read more

FRC seeks members, views for stakeholder reporting panel

first_imgThe UK Financial Reporting Council has put out a call for interested parties to take part in a new project under the auspices of its Financial Reporting Lab.The initiative will examine corporate disclosures in the UK about so-called company stakeholders.In a statement, the FRC said the project will include corporate reporting obligations under section 172 of the Companies Act 2006.With effect from 1 January 2019, UK companies have been required to report specifically on their compliance with that section of the Act. It said that company directors must act in such a way as to “promote the success of the company for the benefit of its members as a whole”.In doing so, the section goes on to explain that directors should consider a number of factors and stakeholders such as the firm’s workforce, its suppliers and even its impact on the wider environment.Back in 2017, Pensions & Investment Research Consultants Limited and the FRC found themselves embroiled in a row involving the UK Parliament over whether or not the watchdog could compel companies to report on their compliance with s172.Climate change campaigners ClientEarth have also argued that companies are not complying with the law and filed two regulatory complaints with the FRC.The government subsequently issued The Companies (Miscellaneous Reporting) Regulations 2018 to force companies to explain how they have complied with s172.In addition to s172, the new FRC Reporting Lab project will initially look at a range of other issues linked to stakeholder reporting such as: how companies engage with stakeholders;which aspects of reporting it is that companies find most challenging; and what lessons can be drawn from relevant international developments.Investors and companies that want to take part in the project can contact the FRC at [email protected] agency said it is also interested in hearing views from other relevant parties such as stakeholder representative bodies.To read the digital edition of IPE’s latest magazine click here.last_img read more

Ighalo deserves Man United permanent deal – Hargreaves

first_imgIghalo joined United on a six-month loan deal from Chinese Super League outfit Shanghai Shenhua in January and has proved doubters wrong with his performances.The 30-year-old has scored four goals in eight appearances for Ole Gunnar Solskjaer’s men since his arrival at the club.Ighalo’s loan deal at United will expire at the end of the month, with the former Watford striker now expected to return to China.Shenhua are reportedly willing to allow Ighalo join United for £20m, and it remain to be seen if the former Premier League champions will meet their demands especially with Marcus Rashford back from injury.Hargreaves expects United to pursue a permanent for Ighalo despite having Rashford and Anthony Martial at their disposal.“I think he’s been a good fit for Man United and when you sign players you’ve got to get the right fit,” Hargreaves told talkSPORT.“It’s not always about getting the best name, it’s about getting the guy that you don’t have that you need.“He was somebody that whoever signed him hats off to you, because he’s given them something different.Read Also: Video: Ronaldo showcases medals, silverware in his museum“Hopefully he stays but there’s the whole Sanchez situation when he comes back, Martial and Rashford, he’s fit as well, Bruno [Fernandes] and [Paul] Pogba – you’ve got to get them all into a team, with Daniel James as well.“So he’s been good, really good. I’m sure they’ll try, if it’s sensible, keep him longer. I’d be surprised if he left.”FacebookTwitterWhatsAppEmail分享 Loading… Former Man United star Owen Hargreaves believes Odion Ighalo deserves to join Manchester United on a permanent transfer after the Nigerian stellar displays for the Red Devils.Advertisementcenter_img Promoted ContentThe Very Last Bitcoin Will Be Mined Around 2140. Read More10 Risky Jobs Some Women Do7 Theories About The Death Of Our UniverseCan Playing Too Many Video Games Hurt Your Body?7 Black Hole Facts That Will Change Your View Of The Universe6 Extreme Facts About Hurricanes20 Amazing Facts About The Daenerys Of The House Of Targaryen2020 Tattoo Trends: Here’s What You’ll See This Year6 Ridiculous Health Myths That Are Actually True8 Things You Didn’t Know About Coffee7 Reasons Why You Might Want To Become A VegetarianWhich Country Is The Most Romantic In The World?last_img read more

Aug. 18 is deadline for Super Nationals pit stall reservations

first_imgBOONE, Iowa – Friday, Aug. 18 will be the final day to make pit stall reservations for the IMCA Speedway Motors Super Nationals fueled by Casey’s.Pit stall applicants must be licensed IMCA members and have pre-registered for the Sept. 4-9 Super Nationals at Boone Speedway.“We are still taking pit stall applications but they are filling in quickly,” observed IMCA President Brett Root. “The size of their hauler, the division the driver races in and the nights they will be racing are mandatory requirements for us to know.”“We are doing all we can to accommodate requests for pit stalls,” he continued.Pit stall confirmations will be e-mailed to drivers on Aug. 19 and 20. Drivers should bring those confirmations with them to Boone Speedway to make the parking process easier.“There are still plenty of non-reserved stalls available,” Root said. “Boone Speedway has added an additional 17 acres of camping, grandstand parking and pit parking for the 2017 event.”last_img read more